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2026 Week 4 college football odds, picks, predictions, best bets: Take Texas A&M to cover vs. LSU

2026 Week 4 college football odds, picks, predictions, best bets: Take Texas A&M to cover vs. LSU

cbssports.com 26.09.2026 15:09 4 views
SportsLine's model reveals its Week 4 college football picks and best bets for Saturday, September 26

Lane Kiffin is coming off his first loss as the head coach of the LSU Tigers, but he'll look to avoid back-to-back defeats when the 10th-ranked Tigers host the No. 23 Texas A&M Aggies on Saturday at 7:30 p.m. Texas A&M highlights a loaded Week 4 college football schedule, which also features other marquee matchups like No. 1 Texas vs. No. 14 Tennessee, No. 17 Iowa vs.

No. 18 Michigan, No. 4 Ole Miss vs. No. 21 Florida and No. 20 Oregon vs. According to the latest college football odds, LSU is favored by 8.5 points at home.

The latest college football lines list the over/under for total points scored as 51.5. SportsLine's advanced computer model is projecting LSU to secure a 27-26 victory at home, helping the Aggies cover the spread in 63% of its simulations. Claim $150 in bonus bets after making a $5 wager with the latest DraftKings promo code: The model is also backing USC (+3.5) to cover the spread against Oregon, while the Under (54.5) hits 59% of the time in Alabama vs.

Other notable Week 4 college football betting lines include Texas vs. Tennessee (+5.5), Ole Miss vs. Florida (-3.5) and Iowa vs.

Before locking in your Week 4 college football picks, be sure to check out the top college football betting picks from SportsLine's advanced computer model. Bet on college football with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets: The model simulates every FBS game 10,000 times. It is off to a profitable 22-19 start on all top-rated college football picks at betting sites so far this season, and it has been upgraded for the 2026 season to better factor in the transfer portal.

Anybody following its picks on college football betting sites could have seen strong returns. Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook here: Combining the model's three picks into a Week 4 college football parlay would result in a payout of +585 (risk $100 to win $585). Bet it now at FanDuel Sportsbook and get up to $250 in bonus bets: Texas A&M has won three of its last four meetings against LSU, including a 49-25 victory on the road against the Tigers in 2025.

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