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Chiefs vs. Broncos odds, picks, predictions: Betting preview, best bets for Monday Night Football, NFL Week 1

Chiefs vs. Broncos odds, picks, predictions: Betting preview, best bets for Monday Night Football, NFL Week 1

cbssports.com 14.09.2026 15:45 1 views
Best bets and betting preview for Broncos vs. Chiefs on Monday Night Football

The AFC West takes center stage on Monday Night Football for a showdown between the Kansas City Chiefs and Denver Broncos. Denver is coming off a 14-3 campaign, while Kansas City went 6-11 in its first losing season in 13 years under head coach Andy Reid. You can bet on Chiefs vs.

Broncos using the latest DraftKings promo code, where new users get $200 in bonus bets after your first $5 wager: Kickoff for Chiefs vs. Broncos is set for 8:15 p.m. ET at Arrowhead Stadium in Kansas City.

SportsLine's proven computer model and team of NFL experts have analyzed Broncos vs. Chiefs and revealed two best bets, and you can also read our NFL betting preview for Monday Night Football. Broncos at FanDuel and get $350 in bonus bets: The Chiefs are hoping to get off to a strong start this season after going 6-11 last year.

Star quarterback Patrick Mahomes tore his ACL and LCL in Week 15 last year, but he is expected to return exactly nine months after suffering the injury. He has the most career passing yards per game (285.2) in NFL history. Broncos quarterback Bo Nix suffered a broken ankle in a playoff win over Buffalo last season after leading the team to 14 wins, which is tied for the most by a first or second-year quarterback in league history.

He led eight game-winning drives in 2025, including the playoffs. The Chiefs are 2.5-point home favorites in the Chiefs vs. Broncos odds, with the over/under at 43.5.

Claim $200 in bonus bets after your first $5 wager at DraftKings here: "All the talk is about Patrick Mahomes returning for Week 1 but I'm more interested in the big uglies. I expect the Broncos to dominate this game in the trenches," SportsLine expert Thomas Casale said. "Denver has my top-rated offensive line entering the season.

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