The Kansas City Chiefs will look to make it two primetime wins in a row when they battle the Indianapolis Colts on 'Sunday Night Football' in Week 2. Kansas City opened the regular season with a 31-10 thrashing of the Denver Broncos on Monday night, while Indianapolis dropped a 41-23 decision to the Baltimore Ravens this past Sunday. The Colts (0-1), who finished third in the AFC South at 8-9 a year ago, have lost eight consecutive games dating back to last season.
The Chiefs (1-0), who finished third in the AFC West at 6-11, are looking to reach the postseason for the 11th time in 12 years. Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: Kickoff is set for 8:20 p.m. ET from GEHA Field at Arrowhead Stadium in Kansas City, Mo.
Colts odds have Kansas City as 6.5-point favorites, while the over/under for total points scored is 46.5. Before making any Colts vs. Chiefs picks or 2026 NFL Week 2 predictions, be sure to see what the SportsLine projection model has to say.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns.
Now, the model has zoned in on Colts vs. You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Chiefs vs.
Colts: New to sports trading? Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS: After 10,000 simulations of Colts vs. Chiefs, the model is going Over 47.5 points at betting apps.
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