Having just two teams on byes last Sunday likely didn't affect anyone's Fantasy football lineups too much. The same can't be said for this week. Four teams having off undoubtedly shuffles the Week 6 Fantasy football rankings and creates some anxious Fantasy start-sit decisions.
Fortunately, some players who got off to slow starts have come on strongly as of late like Drake Maye, Jordan Love, Bucky Irving and Malik Nabers to create a deeper pool of top options to select from with Week 6 Fantasy football picks. Injuries have piled up around the league, with Lamar Jackson (ankle) and Jalen Hurts (blood clot) headlining the list of quarterbacks who will be out this week. Caleb Williams (hamstring) did practice this week and is expected to play, though he does have a questionable tag officially.
At the skill positions, Tyler Warren (groin), Quinshon Judkins (ankle) and Chris Olave (illness) are among the players heading into Sunday who are listed as questionable. Before setting your Week 6 Fantasy football lineups, be sure to check out the Week 6 Fantasy football rankings from the proven computer model at SportsLine. When it comes to ranking players, SportsLine's model beat human experts in Fantasy football for the past several seasons, especially when there were big differences in ranking.
Over the course of a season, that could literally be the difference between winning your league or going home empty-handed. The same model has a proven track record providing Fantasy football tips, including being ahead of the curve on players like A.J. Brown, Jonathan Taylor, Derrick Henry, Christian McCaffrey, Alvin Kamara and Jahmyr Gibbs.
Anybody who banked on players like those could have made a run at their league title. Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 6 of the 2026 NFL season. Head to SportsLine now to see them.
One surprise in Week 6: The model isn't high on Raiders quarterback Kirk Cousins, despite him ranking sixth in Fantasy points for QBs this year. The veteran overachieved to start the year but is coming off his worst game with just 243 passing yards and 1 touchdown versus New England. Cousins is trending in the wrong direction as after having 3 passing TDs in each of the first three weeks, he then had two scores in Week 4 and then one in Week 5.
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