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Indiana vs. Northwestern prediction, odds, time: 2026 Week 4 college football Friday picks by proven model

Indiana vs. Northwestern prediction, odds, time: 2026 Week 4 college football Friday picks by proven model

cbssports.com 24.09.2026 17:42 3 views
The SportsLine Projection Model has revealed its best bets for the Northwestern Wildcats vs. Indiana Hoosiers in a Big Ten opener Friday night

The defending national champion Indiana Hoosiers begin defense of their Big Ten championship on Friday night when they face the Northwestern Wildcats. Both the Hoosiers (3-0) and Wildcats (2-0) have been mostly untested thus far. The Hoosiers and Wildcats average 461 and 460 yards per game, respectively.

Indiana owns a 19-game win streak and a defense allowing 5.3 points per game. TCU transfer QB Josh Hoover has 10 TDs and zero INTs. IU has won the last two matchups handily, snapping a string of dominance (9 of 10) by Northwestern.

Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: Kickoff is set for 8 p.m. ET at Memorial Stadium in Bloomington, Ind. The Hoosiers are 21-point favorites in the latest Northwestern vs.

The over/under for total points is 49.5. Before making any Northwestern vs. Indiana picks, check out the Northwestern vs.

Indiana predictions from the SportsLine Projection Model. The model simulates every FBS game 10,000 times. It is off to a profitable 22-19 start on all top-rated college football picks at betting sites so far this season, and it has been upgraded for the 2026 season to better factor in the transfer portal.

Anybody following its picks on college football betting sites could have seen strong returns. Now, the model has set its sights on Northwestern vs. You can visit SportsLine now to see the picks.

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