Without question, the most-hyped college football game on the schedule this week -- if not perhaps most hyped the entire season -- is No. 7 LSU at No. 8 Ole Miss on Saturday with a 7:30 p.m. All the talk will of course be about Lane Kiffin's return to Oxford, but with that glaring-hot national spotlight, Rebels QB Trinidad Chambliss could make a major Heisman Trophy statement, as he's currently priced as a +1300 fifth-favorite via DraftKings. Bet on college football at DraftKings, where new users get $200 when they spend $5+: Even better, it's the first meeting with both schools ranked in the AP Top 10 since 1962.
Home teams have won in four straight regular season Top-10 meetings in the FBS overall and are 30-12 (.714) in these matchups since 2020. At -3, LSU is taking 95% of handle and 71% of early-week action, with similar numbers on Tigers at -155. On the total of 58.5, there are heavy leans to the Over.
It will be scorching hot in Oxford on Saturday afternoon but looks good at night: A few clouds from time to time. Winds light and variable. You can try college football betting on the best sports betting apps, but first you should check out the SportsLine Projection Model for picks on games from both the simulations and our experts.
We have a strong play here for those who want to get into parlay betting for LSU vs. DrafKings price: +129 (subject to change) Say what you want about Kiffin, and many have, but the guy can coach and has an eye for talent. He went 55-19 in six seasons at Ole Miss before leaving -- and taking many assistants -- before last season's College Football Playoff.
Those 55 wins are the third-most in school history, and Kiffin's winning percentage of .743 was second-best (minimum 10 games). His leaving marked only the sixth instance of a head coach bolting an AP Top 10 team for another FBS school before the end of a season in history. The last had been Mario Cristobal from Oregon to Miami in 2021.
Kiffin became the 10th head coach to leave one SEC school for another, and he's the first to face a team he previously led to the CFP. Only Nick Saban (with Alabama vs. LSU) and Chip Kelly (with UCLA vs Oregon) faced a team they had previously led to the BCS National Championship Game, and Saban (2007) and Kelly (2018) lost their respective first meetings against their ex-schools.
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