The first NFL Sunday of the year is here, and it's time to shift our attention from our loved ones to our sports betting apps. There are plenty of ways to win or lose money when it comes to betting on the NFL, but one of the most popular options has become anytime touchdown scorers. One reason is that the odds are juicier.
If you're a Los Angeles Chargers fan and think Keaton Mitchell is going to be Mike McDaniel's De'Von Achane, maybe you'll take a flier on him to find the end zone at +340. If you think rookie running back Jeremiyah Love scores a touchdown in his first NFL game, +205 doesn't seem like a bad bet. Maybe Kyler Murray runs in a touchdown in his first game with the Minnesota Vikings.
Below, we will break down five anytime TD bets to consider for Week 1. These will not be predictable choices like a Bijan Robinson or Jahmyr Gibbs score that offer zero value, but they won't be wild long-shots such as a team defense. Let's begin with a wide receiver that dominated right off the bat as a rookie last year.
There's no more Mike Evans in Tampa, and I'm expecting second-year wide receiver Emeka Egbuka to play a major role in Baker Mayfield's offense. The Ohio State product started off his rookie season hot, catching 25 passes for 445 yards and five touchdowns in his first five games of the year. He can get off to a similar start in 2026 against a Cincinnati Bengals defense that still has a few questions to answer.
Check out this insane stat I discovered: Saquon Barkley has scored at least one touchdown in EIGHT STRAIGHT meetings vs. I've seen Barkley anytime TD listings around -200 in the past, so getting him at -115 almost qualifies as "value." The Philadelphia Eagles are debuting a new-look offense on Sunday, but expect Barkley to still be an important piece of this attack as both a runner and receiver. Plus, don't forget that the Washington Commanders had what was statistically the worst defense in the NFL last year, allowing 384 yards of total offense per game.
I don't bet on first touchdown scorers, but Barkley at +500 is definitely an option to consider as well. Lamar Jackson's disappointing 2025 campaign was headlined by a hamstring injury that held him back even when he returned to the lineup. His 349 yards rushing marked a career low, as did his two rushing touchdowns.
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