The calendar has flipped to October, and Week 4 of the NFL season has arrived. It's a loaded slate as the contenders look to separate from the pretenders this month. This week specifically features the first of the three London Games this year — making it the first extra-long Sunday of the season — and a division rivalry renewed on "Monday Night Football." As we do every week, we've collected all of the best picks and gambling content from CBSSports.com and SportsLine.
We've put them in one place, so you can get sports betting picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. All NFL betting courtesy of SportsLine consensus. Which picks can you make with confidence this week?
And which Super Bowl contender goes down hard? Visit SportsLine, as its incredible model simulates every NFL game 10,000 times and is up almost $7,000 for $100 players on top-rated NFL picks since its inception. ET (NFL Network), stream on fubo (try for free) Open: Commanders -1.5, O/U 48.5 "Both teams won for the first time last week and now head to London to play this week.
Then the Colts defense showed improvement last week, while the Commanders defense made some big plays. Look for the Colts and Commanders to both score a lot, but it's the Colts who will win it late." Pete Prisco likes the Colts to win a 31-30 thriller in London, and to check out the rest of his picks, click here. ET (CBS), stream on Paramount+ (click here) Open: Bills -3, O/U 49.5 "The post-Super Bowl hangover continued for the Patriots in an ugly 35-6 road loss to the Jaguars.
We'd be surprised if we didn't at least see a respectable outing against a Bills side that, despite its 3-0 record, was fortunate to escape an error-filled performance against the downtrodden Chargers in a 24-16 Week 3 victory." But does that "respectable outing include covering the spread? To see all of SportsLine expert Josh Nagel's teaser selections, click here. ET (FOX), stream on fubo (try for free) Open: Bears -8.5, O/U 45.5 "All hail Case Keenum after his sublime performance on Monday night.
You can't tell me that Ben Johnson isn't a top-10, if not higher, coach in the NFL right now. Brilliant game plan with a third-string QB in Week 3. The Jets are improved and could be a playoff team within the next two years, but I'm not sure that they are much better than a six or seven-win team in 2026.
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