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Panthers vs. Lions picks, prediction, player props: Expert's NFL Week 4 best bets for Sunday Night Football

Panthers vs. Lions picks, prediction, player props: Expert's NFL Week 4 best bets for Sunday Night Football

cbssports.com 05.10.2026 01:01 4 views
Targeting a high-scoring shootout in Charlotte, our betting picks back Jahmyr Gibbs in the passing game and Darren Waller to stay heavily involved

The NFL returns to Charlotte for a Sunday night prime-time game for the first time in more than a decade, and with the Lions coming to town to face the Panthers, we should be in store for some fireworks. Detroit is a 3.5-point favorite in the latest Lions vs. Panthers odds from DraftKings Sportsbook, and the Over/Under on the game total is set at 47.5 points.

Bet on Sunday Night Football at DraftKings, where new users get $150 in bonus bets after they spend $5+: One major downside for the Panthers is that they have been ravaged by injuries recently, including losing their best offensive lineman, Damien Lewis, for a while. They also placed both starting cornerbacks on IR, so things could be dicey against this explosive Lions offense. Get a $55 bonus after $25 in trades by claiming the latest Kalshi promo code CBSSPORTS55 here: This line has climbed a full point over the last 24 hours, and that probably involves the weather.

It was supposed to dump rain all day Sunday in North Carolina, but we're now staring down just some chill in the air and what should be a fun one. The Lions' last appearance in prime time cashed everyone out with the explosive matchup against the Bills. I'm not expecting Carolina to perform like Buffalo did, but the Panthers are highly susceptible to being dragged into shootouts if their opponent starts to sling the ball around.

Given the dearth of defensive backfield talent out there for Carolina, I fully expect the Lions to take advantage and throw the ball downfield. Carolina should be able to answer and we should get points galore. Bryce Young is going to be forced to pass the ball in this one, and that should bode well for Waller, who's been a surprisingly impressive target for the Panthers as a late addition to the roster.

He broke out in Week 2 with a pair of scores then was rewarded with eight targets in Week 3 against the Browns. I'd expect him to see close to that many again Sunday night, making this number just way too low for how much Bryce looks his way, especially if Jalen Coker ends up inactive tonight. Gibbs is the unquestioned best running back in football right now and has really rewarded anyone who took him first overall in fantasy.

But he's not just a great runner, he's also an elite receiver, and in a game that should be a shootout with Jared Goff looking to exploit the Panthers defense, I'd expect Gibbs to be plenty involved in the pass game as well. 40 receiving yards feels very, very doable for the superstar. Bet on NFL player props and more at BetMGM: If Williams wasn't having such a meh year so far, this number wouldn't be north of 2-1. But he's been just OK thus far, and as such we're getting a great price.

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