A matinee on the Wednesday MLB schedule will see Paul Skenes back on the mound as his Pittsburgh Pirates host the Detroit Tigers. Skenes (9-11, 3.88 ERA) had this start pushed back three days after struggling in recent outings as Pittsburgh (62-66) has split its last 10 games. Detroit will send Jackson Jobe (1-1, 6.23 ERA) to the mound as the righty makes his third start of the year.
This is the rubber match after Detroit took Monday's contest, 8-5, with Pittsburgh then taking Tuesday's matchup 4-1. Visit our DraftKings promo code review and get $150 in bonus bets instantly as a new user after $5+ in wagers here: First pitch is at 12:35 p.m. ET from PNC Park in Pittsburgh.
The Pirates have won five of the last six meetings. Pirates odds have Pittsburgh as the -150 favorite on the money line (risk $150 to win $100), while the over/under is 8. Before making any Pirates vs.
Tigers picks or MLB predictions, be sure to see the Tigers vs. Pirates predictions and betting advice from SportsLine's proven computer model. The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 22 of the MLB season on a sizzling 49-31 run on all top-rated MLB picks.
It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anyone following its MLB betting picks at sportsbooks and on sports betting sites could have seen strong returns. Now, the model has set its sights on Tigers vs.
Pirates and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Pirates vs.
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