A loaded Week 1 NFL schedule is packed with marquee matchups, including an NFC East bout between the Dallas Cowboys and New York Giants on Sunday Night Football. Cowboys set for 8:20 p.m. The Giants have struggled mightily against Dallas in recent years, losing nine of the past 10 meetings.
Kalshi, one of the largest NFL prediction markets, prices the Cowboys at $0.61 per share to beat the Giants, who are trading at $0.40 per share. More than 47.5 points scored is trading at $0.51 per share. Trade $25 and get a $25 bonus here with the Kalshi promo code CBSSPORTS: The NFL Week 1 schedule also features several other division rivalries, including an NFC North battle between the Green Bay Packers and Minnesota Vikings on Sunday afternoon.
Green Bay leads the all-time series 67-61-3, but the Vikings have fared well in recent years, winning six of the past 10 meetings. The Vikings, who are coming off a 9-8 campaign in 2025, signed former No. 1 overall pick Kyler Murray this offseason to lead the offense. All of the updated Week 1 NFL prediction market prices are listed below, and SportsLine's advanced computer model has all the NFL trading advice and NFL predictions you need to make the best Week 1 NFL picks now.
The model entered Week 1 on a 47-32 run on top-rated picks dating back to 2024. Anybody following its picks on NFL prediction markets and prediction market apps could have seen strong returns. Now, it has turned its attention to the latest Week 1 NFL prediction market prices and locked in predictions for every NFL matchup.
Trade on the NFL here with the Polymarket promo code CBSSPORTS and get a $50 bonus after a $10 deposit: Two teams that won their respective divisions are set to square off when the Carolina Panthers host the Chicago Bears in Week 1. The Bears are coming off a season in which they finished 11-6 under their first-year head coach Ben Johnson. Quarterback Caleb Williams played well in his first season under Johnson, finishing with 3,942 passing yards, 27 touchdowns and seven interceptions.
Williams finished the year throwing two or more touchdowns in eight of his final nine contests, which includes two playoff games. Meanwhile, the Panthers topped the NFC South despite posting an 8-9 record. Panthers QB Bryce Young is coming off his best season as a professional, throwing for 3,011 yards and 23 touchdowns.
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