The 2026 NFL Kickoff Game is set to take place on Wednesday when the Seattle Seahawks battle the New England Patriots in a Super Bowl LX rematch. Kickoff from Lumen Field in Seattle is set for 8:20 p.m. Kalshi, one of the largest NFL prediction markets, prices the Seahawks at $0.62 per share to beat the Patriots at home, while New England is trading at $0.39 per share.
Trade $25 and get a $25 bonus here with the Kalshi promo code CBSSPORTS: The NFL Week 1 schedule also features several division rivalries, including an NFC North battle between the Green Bay Packers and Minnesota Vikings on Sunday afternoon. Green Bay leads the all-time series 67-61-3, but the Vikings have fared well in recent years, winning six of the past 10 meetings. The Vikings, who are coming off a 9-8 campaign in 2025, signed former No. 1 overall pick Kyler Murray this offseason to lead the offense.
All of the updated Week 1 NFL prediction market prices are listed below, and SportsLine's advanced computer model has all the NFL trading advice and NFL predictions you need to make the best Week 1 NFL picks now. The model entered Week 1 on a 47-32 run on top-rated picks dating back to 2024. Anybody following its picks on NFL prediction markets and prediction market apps could have seen strong returns.
Now, it has turned its attention to the latest Week 1 NFL prediction market prices and locked in predictions for every NFL matchup. Trade on the NFL here with the Polymarket promo code CBSSPORTS and get a $50 bonus after a $10 deposit: The first game of the 2026 NFL season features a Super Bowl LX rematch, a game which Seattle won 29-13. The Seahawks will enter Wednesday's contest full of confidence because the defending Super Bowl champions are 16-5 in NFL Kickoff games, which began in 2004.
The Seahawks return several key starters from last year's Super Bowl-winning squad, including star wide receiver Jaxon Smith-Njigba. Smith-Njigba led the league in receiving yards a season ago, recording 119 catches for 1,793 yards and 10 touchdowns. His production was a big reason why the Seahawks averaged 28.4 points per game last season, which ranked third in the NFL.
The Patriots will be looking for revenge on Wednesday, and New England bolstered its already efficient offense with the additions of AJ Brown and Romeo Doubs. Brown recorded over 1,000 receiving yards and at least seven receiving touchdowns in each of his past four seasons with the Eagles, while Doubs averaged a whopping 13.2 yards per reception last season. The SportsLine Projection Model has Seattle winning this matchup at home by a score of 28-18.
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