Home underdogs always elicit interest with NFL picks, and there's a bevy of them to choose from with your Week 2 NFL picks. The Jets are 4.5-point underdogs as they'll host the Packers, while the Cardinals have that same number as they welcome Seattle to town. The slimmest Week 2 NFL spread has the Falcons as 1.5-point home dogs against Carolina, while the biggest home underdogs are the Titans (+7), with the Eagles coming to town.
The extra motivation that comes with being doubted in your own home stadium could also make several players from these underdogs attractive in NFL player props or in Week 2 Fantasy football lineups. Trade the NFL at Polymarket here: A Week 2 NFL parlay involving only underdogs could also be of interest, both with the spread, or if you're really bold, backing these teams on the money line at NFL betting sites. Four underdogs won straight up in Week 1, including the Jets and Cardinals, as your Week 2 NFL betting strategy won't be complete without considering the longshots.
If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 2, SportsLine has you covered with its proven model, Machine Learning Model and team of experts. Paramount+ Premium is now included with every SportsLine membership! Watch the NFL on CBS, UFC, Champions League and more than 40,000 episodes and movies.
Join right here to get both for one low price. SportsLine's model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model has built a five-team parlay for Week 2 that pays nearly 25-1, and one of the legs is taking Seattle (-4.5) to cover versus Arizona on Sunday at 4:25 p.m.
The model has the Seahawks covering in well over 60% of simulations, and the rest of the five-team parlay can be found here. Mike McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account.
In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. For the main Sunday slate in Week 2, McClure likes Bears TE Colston Loveland as one of his top picks. Here are his complete Week 2 NFL DFS picks.
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