Week 2 of the 2026 college football season kicks off on Thursday, Sept. 10 but most of the action will take place on Friday, Sept. 11 and Saturday, Sept. 12. There are plenty of marquee matchups available for those interested in college football betting to target, including No. 1 Ohio State facing off against No. 4 Texas. Do either the Buckeyes or Longhorns feature in Week 2's top parlays involving favorites and underdogs?
SportsLine football expert Mike Tierney outlines his top parlay bets for favorites and underdogs on the Week 2 slate. A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Tierney has covered the NFL for decades and reported from seven Super Bowls. He is 320-271-16 in the NFL the past four seasons, returning $1,867 to $100 players.
That includes Mike going 130-101 ATS (56.3 percent) the past two seasons. And over the past two college football seasons, Tierney is 121-103. Here are his best parlays for Week 2.
Follow Tierney's college football bets with the latest DraftKings promo code and get $200 in bonus bets when you spend $5+: Welcome to the weekly feature where we recommend three-team money line betting parlays on Friday's and Saturday's college football card. You will see one set of games exclusively with favorites, followed by a set consisting entirely of underdogs for those feeling especially daring. Each game is accompanied by the most favorable line selected from the half-dozen sportsbooks recognized by Sportsline.
By the time you read this, some numbers might have shifted slightly. This is quite a hefty number with an underdog that breezed to a 70-7 win in its opener. Yet A&M's 50-0 whitewashing of Missouri State might have been more laudatory.
The stingy Aggies' defense allowed all of 67 yards. Arizona State must contend with QB Marcel Reed, whose running and throwing presents a pick-your-poison dilemma for the defense. Because they are dashing off after the final horn to London, the site of next week's game, the Sun Devils consented to a 9 a.m.
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