This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility: Intense exercise during long spaceflights helps maintain heart structure and function within a range needed to tolerate the low-gravity environment of Mars, a study co-led by a UT Southwestern Medical Center researcher suggests. The findings, published in Circulation, not only address an issue critical to future space missions but could also lead to better interventions to improve heart health on Earth.
"Our previous studies had demonstrated that the heart atrophies in both bed rest and in space—it becomes smaller and stiffer—and we were concerned that could be a problem over long-duration spaceflight, especially for missions to Mars. Our findings suggest that the exercise countermeasures we already have in place are enough to keep the heart in good working order for Mars' gravitational loads," said Benjamin Levine, M.D., professor of internal medicine in the Division of Cardiology at UT Southwestern, where he holds a distinguished professorship in exercise sciences. He is the founding director of the Institute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas, where he holds the S.
Finley Ewing Chair for Wellness and the Harry S. Moss Heart Chair for Cardiovascular Research. Levine is a sports cardiologist who treats athletes with cardiovascular problems from around the world and serves as a consultant to the NCAA, National Hockey League, National Football League, U.S.
Olympic Committee and U.S. He also has a background in space medicine, having served as a co-investigator on four Spacelab missions and the Russian Mir space station and as principal investigator on the International Space Station. His work with astronauts has translated to an area of clinical expertise: patients with "gravity diseases" such as syncope (fainting) and orthostatic intolerance (the inability to stand up and withstand the effects of gravity on Earth).
One of Levine's recent efforts was co-leading NASA's Integrated Cardiovascular Study (ICV), which investigated how long-duration spaceflight affects heart structure, function and electrical activity, with the goal of defining risks and guiding countermeasures for future missions. In a recent phase of the ICV, he worked with collaborators including Michael Bungo, M.D., of the McGovern Medical School at UTHealth Houston, and James Thomas, M.D., of the Northwestern University Feinberg School of Medicine, to answer a critical question: How does the heart remodel itself over the course of a long spaceflight? Although the ICV had previously evaluated the structure and function of astronauts' hearts before and after their missions on the International Space Station, little was known about the time in between—particularly what might happen after landing on a planet like Mars with reduced gravity (Mars' gravity is about 3/8 that of Earth's).
Earlier studies on space-induced cardiac remodeling relied on cardiac MRI, a tool impossible to use during spaceflight. For the current research, the team turned to echocardiography with Doppler ultrasound, which allowed them to evaluate the heart's anatomy and how efficiently it pumped blood. The researchers worked with 14 astronauts, nine male and five female, each of whom orbited on the International Space Station for about six months—roughly the duration of a flight to Mars.
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