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Patriots vs. Seahawks picks, odds, predictions, best bets: Betting preview for 2026 NFL Kickoff Game

Patriots vs. Seahawks picks, odds, predictions, best bets: Betting preview for 2026 NFL Kickoff Game

cbssports.com 10.09.2026 01:52 21 views
Best bets and betting preview for Patriots vs. Seahawks in 2026 NFL Kickoff Game on Wednesday

Football fans will be treated to a marquee matchup on Wednesday, with the Seattle Seahawks hosting the New England Patriots in a Super Bowl LX rematch. The Seahawks hoisted the Lombardi Trophy in February after knocking off the Patriots, 29-13. The Seahawks enter tonight's contest as a 3.5-point favorite, according to the latest NFL betting odds.

Patriots running back TreVeyon Henderson (ankle) is inactive against the Seahawks. You can bet on the NFL Kickoff Game using the latest DraftKings promo code, where new users get $200 in bonus bets after your first $5 wager: Kickoff for Seahawks vs. Patriots is set for 8:20 p.m.

SportsLine's team of NFL experts have analyzed Patriots vs. Seahawks and revealed their three best bets, and you can also read our NFL betting preview for the NFL Kickoff Game. Patriots at FanDuel and get $350 in bonus bets: The Seahawks and Patriots are meeting in a rematch of last season's Super Bowl, marking just the third such rematch in Week 1 of the following season.

This is also just the fifth NFL game on a Wednesday since 1950, and the first since there were a pair of games on Christmas in 2024. Defending Super Bowl champions are 16-5 in NFL Kickoff games since they were introduced in 2004. Seattle returns quarterback Sam Darnold and wide receiver Jaxon Smith-Njigba, while Mike Macdonald is eyeing another strong campaign after becoming the third-youngest head coach to win the Super Bowl.

New England is led by MVP runner-up Drake Maye, who became the second-youngest quarterback to start the Super Bowl. The Seahawks are 3.5-point home favorites in the Seahawks vs. Patriots odds, with the over/under at 44.5.

Claim $200 in bonus bets after your first $5 wager at DraftKings here: "I like this spot for AJ Barner who looks like an ascending player for the defending champion Seattle Seahawks," SportsLine expert Alex Selesnick said. "Barner had a strong rookie season and was a reliable target for Sam Darnold. He dealt with numerous injuries which were addressed in the offseason.

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