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Prisco's Week 1 NFL picks: Seahawks dominate Patriots once again, Bills end skid vs. Texans

Prisco's Week 1 NFL picks: Seahawks dominate Patriots once again, Bills end skid vs. Texans

cbssports.com 09.09.2026 13:19 5 views
Pete Prisco reveals all of his season-opening picks, including a healthy dose of Patrick Mahomes in a win over the Broncos

How will returning injured players show in their first game back? That makes picking this week's games even tougher than other weeks. I had a good season in 2025, so let's see if that can carry over this year.

The way I see it, if you can navigate the early weeks and settle in for October and November, you have a chance at a good season. So let's start strong -- even in the face of Week 1 adversity. This rematch of the February Super Bowl will go much like that game.

The Seahawks will dominate. Opening on the road in this stadium is a tough ask for any team. The Patriots' offense didn't play well in the postseason and didn't against Seattle in the Super Bowl.

That plays out again here. The Rams are the trendy Super Bowl pick by most because of all the stars on the roster. But the 49ers have stars as well.

These two have played a lot of good, close games. This will be no different. The Rams will win it late, but the 49ers will hang around.

The Falcons have quarterback issues with Tua Tagovailoa named the starter. The Steelers are trotting out Aaron Rodgers for the start of his final season. With the Falcons having their two top pass rushers down, this will be a chance for Rodgers to start the season right.

Extract — continue reading at the source.

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